Figure 6.

Promoter methylation of candidate genes. a. Promoter DNA methylation (balls on a stick) has been reported to regulate gene expression, for example by preventing transcription factors (TF) from binding to the promotor. b. According to Gene Set Enrichment analysis, promoters of candidate genes associated with reproductive phenotypes in fish in the literature (Table S3) are significantly more often differentially methylated between the territorial and the non-territorial phenotype than the average gene.