Table 3.
Number of strains sequenced in this study and identified from GenBank with different nucleotides at the start codon for pre-C, between positions 1814–1816.
| N Strains with Respective Precore Start Codons | ||||||
|---|---|---|---|---|---|---|
| AUG | CUG | ACG | UUG | AAG | AUA | |
| Without known liver disease | ||||||
| HBeAg reactive | 9 | 0 | 0 | 0 | 0 | 0 |
| Anti-HBe reactive | 9 | 2 | 0 | 2 | 1 | 0 |
| Both markers | 2 | 0 | 0 | 0 | 0 | 0 |
| Subtotal | 20 | 2 | 0 | 2 | 1 | 0 |
| With known liver disease | ||||||
| HBeAg reactive | 6 | 0 | 0 | 0 | 0 | 0 |
| Anti-HBe reactive | 4 | 1 | 1 | 1 | 1 | 0 |
| Both markers | 1 | 0 | 0 | 0 | 0 | 0 |
| No HBe marker | 1 | 0 | 0 | 0 | 0 | 0 |
| Subtotal | 12 | 1 | 1 | 1 | 1 | 0 |
| All patients | ||||||
| HBeAg reactive | 15 | 0 | 0 | 0 | 0 | 0 |
| Anti-HBe reactive | 13 | 3 | 1 | 3 | 2 | 0 |
| Both markers | 3 | 0 | 0 | 0 | 0 | 0 |
| No HBe marker | 1 | 0 | 0 | 0 | 0 | 0 |
| TOTAL | 32 | 3 | 1 | 3 | 2 | 0 |
| A1 sequences in GenBank | 237 | 21 | 2 | 6 | 0 | 0 |
| A2 sequences in GenBank | 218 | 3 | 2 | 1 | 0 | 1 |
| A3 sequences in GenBank | 37 | 8 | 1 | 3 | 0 | 0 |