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. 2019 Mar 14;17(3):166. doi: 10.3390/md17030166

Table 1.

Tyrosine phosphatase 1B (PTP1B) and α-glucosidase inhibitory activities of MeOH extract and different solvent-soluble fractions of Symphyocladia latiuscula.

Test Samples Yield (%) a IC50 Values (µg/mL) b ± SD
PTP 1B α-Glucosidase
MeOH 29.62 * 9.01 ± 0.33 e 91.58 ± 9.66 f
CH2Cl2 20.89 6.95 ± 0.94 f 16.76 ± 1.90 h
EtOAc 4.56 2.79 ± 0.11 g 6.71 ± 0.15 i
n-BuOH 10.55 8.72 ± 0.39 e 26.15 ± 0.14 g
H2O 57.36 55.03 ± 1.35 d 867.70 ± 42.20 d
Acarbose c - - 121.33 ± 2.24 e
Ursolic acid c - 6.53 ± 0.23 f -

a Yield (%): The yield (w/w) percentage of each fraction of the MeOH extract. b The 50% inhibition concentrations (IC50, µg/mL), expressed as the mean ± SD of triplicate experiments. c Positive controls. d–i Means with different letters are significantly different on Duncan’s test at p < 0.05. * The % yield calculated on dry alga material.