Date	Event	Description
18 March 2019	New search has been performed	A search of the Cystic Fibrosis and Genetic Disorders Review Group's Cystic Fibrosis Trials Register identified seven new references for potential inclusion in the review. All seven were additional references to the already excluded studies (Griffith 2008; Prayle 2016; Rye 2015; Tullis 2014). Two potential new references were identified from searches of online trial registries and were also excluded (NCT00298922; Uluer 2013).
18 March 2019	New citation required but conclusions have not changed	No new studies or data were included in this updated review, hence our conclusions remain the same.