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. 2019 Mar 28;19(5):4027–4034. doi: 10.3892/mmr.2019.10097

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Copyright: © Yu et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 4. — miR-16 binding with the 3′UTR of ADRB2 gene. (A) Reverse transcription-quantitative polymerase chain reaction analysis of miR-16 expression in cells transfected with different doses of miR-16 mimics. (B) Luciferase analysis of the wild-type ADRB2 3′UTR in cells transfected with different doses of miR-16 mimic. (C) Luciferase analysis of the mutant ADRB2 3′UTR in cells transfected with different dose of miR-16 mimic. *P<0.05 vs. 0 nM miR-16 group. miR, microRNA; UTR, untranslated region; ADRB2, adrenoreceptor β-2.