Table 1.

Comparison of intermittent fasting protocols [8,11].

Energy restriction for two nonconsecutive days and ad libidum intake for other five days.	Eating days—ad libidum food intake. Fasting days—Low or no-energy food intake.	Ad libitum food intake in specific timeframe (~12-h). Night fasting period according to circadian rhythm.
5:2 Protocol	ADF Protocol	TRF Protocol	Days of the Week
Fast	Eat	~12-h	Monday
Fast	Fast	~12-h	Tuesday
Eat	Eat	~12-h	Wednesday
Eat	Fast	~12-h	Thursday
Eat	Eat	~12-h	Friday
Fast	Fast	~12-h	Saturday
Fast	Eat	~12-h	Sunday

Abbreviations: ADF, alternate-day fasting; TRF, time-restricted feeding.