Table 3.
Details of the studied animals.
| Biodistribution + ARG | In Vivo PET/CT | Metabolite Analysis | ||||
|---|---|---|---|---|---|---|
| Atherosclerotic | Control | Atherosclerotic | Control | Atherosclerotic | Control | |
| No. of animals (m/f) | 10 (5/5) | (8/0) | 3 (3/0) | 3 (3/0) | 3 (3/0) | 3 (3/0) |
| Age (months) | 6–8 | 7–11 | 8 | 3 | 9 | 7 |
| High-fat diet (months) | 4–5 | N/A | 4 | N/A | 5 | N/A |
| Weight (g) | 35 ± 7.0 | 44 ± 3.3 | 42 ± 3.4 | 33 ± 2.7 | 38 ± 6.3 | 37 ± 8.3 |
| Injected radioactivity (MBq) | 11 ± 0.95 | 11 ± 2.1 | 4.7 ± 1.1 | 5.4 ± 1.3 | 9.2 ± 1.3 | 11 ± 0.44 |
ARG = autoradiography. Weight is expressed as mean ± SD. For biodistribution and autoradiography at 60 min post-injection, an additional three female mice were studied (characteristics similar to those in the biodistribution + ARG group).