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. 2019 Mar 14;19(5):3527–3536. doi: 10.3892/mmr.2019.10034

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Copyright: © Hu et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 2. — Effects of carvedilol on cardiomyocyte viability and miR-1 expression. (A) Effects of 10 µM carvedilol on cardiomyocyte viability in the presence of 100 µM H₂O₂ for 24 h, as determined by an MTT assay. (B) miR-1 expression in myocardial tissue as determined by RT-qPCR, which was normalized to U6. (C) miR-1 expression in cardiomyocytes as determined by RT-qPCR, which was normalized to U6. All data are presented as relative levels. *P<0.05 vs. Sham or Con; ^#P<0.05 vs. MI or H₂O₂. miR, microRNA; RT-qPCR, reverse transcription quantitative polymerase chain reaction; car, carvedilol; con, control; MI, myocardial infarction.