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. 2019 Mar 21;20(6):1428. doi: 10.3390/ijms20061428

Figure 2.

Figure 2

Effect of RR on pruritus in DNCB-induced NC/Nga mice. (A) Scratching frequency was measured via videotaping mice from above for 20 min. (B) The level of serum IgE was measured using ELISA. (C) Expression of IL-31 in DNCB-induced NC/Nga mice was measured using IHC. Scale bar, 100 μm. (D) Graphical representation of expression of IL-31 in dorsal skin. (E) The level of serum IL-31 was measured using ELISA. Values are expressed as means ± SEM. ### p < 0.001 versus vehicle group; * p < 0.05, ** p < 0.01, and *** p < 0.001 versus DNCB-treated group.