Table 1.
Comparison of the changes in the four groups.
| WT-Chow | WT-MCD | miR-29a-Chow | miR-29a-MCD | |
|---|---|---|---|---|
| Body weight (g) | 27.79 ± 4.10 | 14.69 ± 1.72 a | 24.40 ± 1.81 a | 14.36 ± 0.7 b |
| Body weight gain (%) | 22.63 ± 6.20 | −46.40 ± 13.79 a | 21.06 ± 4.88 | −36.3 ± 6.68 b,c |
| Liver (g) | 1.08 ± 0.21 | 0.56 ± 0.09 a | 0.97 ± 0.21 | 0.49 ± 0.04 b |
| Liver/body weight (%) | 3.88 ± 0.34 | 3.79 ± 0.32 | 4.02 ± 1.02 | 3.41 ± 0.31 |
| AST (U/L) | 73.00 ± 31.00 | 192.6 ± 59.00 a | 65.25 ± 21.41 | 148.09 ± 36.75 b,c |
| ALT (U/L) | 20.00 ± 10.82 | 102.6 ± 92.58 a | 15.75 ± 5.59 | 103.09 ± 54.05 b |
WT, wild type; MCS, methionine-choline-deficient; Data expressed as mean ± standard deviation; a p < 0.05 versus WT-MCS; b p < 0.05 versus miR-29a-MCS; c p < 0.05 versus WT-MCD.