Figure 4.

CyA inhibited Con A-induced liver injury in mice. Mice were treated in the same way as described in Figure 1. The liver injury was assessed by (A–D) the levels of ALT, AST, LDH and TBil in mouse serum (n = 5), also assessed by (E) morphology, (F) liver index (n = 5), (G) H&E stained liver section (bar = 100 μm) and (H) inflammation score (n = 5). White arrow indicates hepatocyte necrosis or apoptosis; black arrow indicates erythrocyte diapedesis; green arrow indicates lymphocyte infiltration. Data were expressed as mean ± SD. * p < 0.05, ** p < 0.01 and *** p < 0.001, versus the model group.