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. 2019 Mar 25;20(6):1489. doi: 10.3390/ijms20061489

Figure 2.

Figure 2

PRGF increased the Aβ42 transport across the cell-based BBB model in-vitro. (A) Concentration-dependent increase in Aβ42 transport across the bEnd-3 cells-based BBB model. Data represented as mean ± SD of 3 independent experiments with n = 4 wells/treatment/experiment. (B) Representative blots and densitometry analysis of Aβ major transport proteins demonstrated a concentration-dependent increase of P-gp and LRP1. Data are presented as mean ± SD of three independent experiments with n = 3 dishes/treatment group/experiment. * p < 0.05, *** p < 0.001 compared to control (CTRL) group.