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. 2019 Mar 16;20(6):1334. doi: 10.3390/ijms20061334

Figure 2.

Figure 2

Bisulfite pyrosequencing quantification of CpG methylation in PFKFB2, CXXC5, and ATPV6V0. (A) Kruskal-Wallis and Dunn’s post-hoc tests were applied to compare non-neoplastic thyroid samples (NT/BTL) and carcinomas from patients with good (TC-GP) and poor prognosis (TC-PP). (B) Comparison between poor prognosis (WDTC-PP) and good prognosis (WDTC-GP) well-differentiated thyroid carcinomas using Mann Whitney test. BIS-PYRO: bisulfite pyrosequencing; NT: non-neoplastic thyroid; BTL: benign thyroid lesions; WDTC-GP: well-differentiated thyroid carcinomas of good prognosis; WDTC-PP: well-differentiated thyroid carcinomas of poor prognosis; ATC/PDTC: anaplastic carcinoma/poorly-differentiated thyroid carcinomas; TC-GP: thyroid carcinomas of good prognosis; TC-PP: thyroid carcinomas of poor prognosis; NS > 0.05; * p < 0.05; ** p < 0.01; *** p < 0.001.