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. 2019 Jan 8;25(8):2019–2024. doi: 10.1002/chem.201804790

Figure 3.

Figure 3

Fragment‐based screening approach for OGFOD1 inhibition: (A) Structures of diketones, triketones, and structurally related compounds used for fragment‐based screening. (B) Inhibitory effect of the fragments on the hydroxylation activity of OGFOD1 (1 μm). The plotted data represent the mean percentage inhibition for the experiment performed in triplicate, whereas the error bars indicate the standard deviation.