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. 2019 Mar 19;11(3):662. doi: 10.3390/nu11030662

Figure 2.

Figure 2

Figure 2

Michaelis–Menten plot of BACE1 inhibition by (a) cardamonin, (d) pinocembrin, and (g) pinostrobin in the presence of different inhibitor concentrations: 0.1 μM (●), 1 μM (○), 5 μM (▼), 10 μM (▽), and 25 μM (■) for cardamonin (a); 1 μM (●), 10 μM (○), 25 μM (▼), 37.5 μM (▽), and 50 μM (■) for pinocembrin (d) and pinostrobin (g). Dixon plot of BACE1 inhibition by (b) cardamonin, (e) pinocembrin, and (h) pinostrobin in the presence of different substrate concentrations: 250 nM (●), 500 nM (○), and 750 nM (▼). Lineweaver–Burk plot of BACE1 inhibition by (c) cardamonin, (f) pinocembrin, and (i) pinostrobin in the presence of different inhibitor concentrations: 0.1 μM (●), 1 μM (○), 5 μM (▼), 10 μM (▽), and 25 μM (■) for cardamonin (c); 1 μM (●), 10 μM (○), 25 μM (▼), 37.5 μM (▽), and 50 μM (■) for pinocembrin (f) and pinostrobin (i).