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. 2019 Mar 19;10(3):235. doi: 10.3390/genes10030235

Figure 2.

Figure 2

CFTR locus and important functional elements. University of California Santa Cruz (UCSC) genome browser displaying CFTR and nearby genes. Airway-selective enhancer elements at −35 kb and −44 kb are shown in dark purple. Intestinal-selective enhancer elements 185 + 10kb (intron 1) and 1811 + 0.8kb (intron 11) are shown in medium purple. Insulator elements at −20.9 kb and + 15.6 kb are shown in dark blue. TAD boundaries at −80.1 kb and + 48.9 kb are shown in medium blue. CFTR promoter is shown in light purple. Other key DNase I hypersensitive sites (DHS) are shown in black.