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. 2019 Mar 19;19(5):4001–4010. doi: 10.3892/mmr.2019.10056

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Copyright: © Shao et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 8. — Nrf2 agonist induces Nrf2/ARE signaling pathway and neurocyte apoptosis in an in vitro model following anti-miRNA-153 treatment. (A) Cell growth, (B) apoptosis rate, (C) cell nucleus, (D) 4′,6-diamidino-2-phenylindole staining (magnification, ×100), (E) caspase-3 and (F) caspase-9 activity. Data are expressed as the mean ± standard deviation (n=3). ^##P<0.01 vs. the control group and **P<0.01 vs. the anti-153 group. Anti-153, miRNA-153-downregulated group; miR/miRNA, microRNA; Nrf2, nuclear erythroid-2 related factor 2; Nrf2 agonist + miRNA-153-downregulated group.