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. 2019 Feb 27;10(3):185. doi: 10.3390/genes10030185

Figure 2.

Figure 2

Hexokinase 2 (HKII) gene expression. q-PCR analysis of HKII mRNA transcript expression in NHL (SU-DHL-4, Raji, Mino, Toledo), breast cancer (MDA-MB-231) and melanoma (MDA-MB-435) cell lines as compared to healthy controls 1 and 2. HKII mRNA levels were increased in NHL cell lines compared to breast cancer cells and healthy controls, however expression levels were not significantly different. HKII mRNA levels were significantly increased in the melanoma (MDA-MB-435) cells when compared to breast cancer cells (MDA-MB-231) (p = 0.044), healthy control 1 (p = 0.045) and 2 (p = 0.037), but not significantly increased compared to the NHL cells. Relative expression normalized to 18S, error bars = SEM and statistical significance calculated using paired Student’s t-test and defined as: * p < 0.05.