Table 2.
Examples of companies offering gene-based dietary recommendations for weight loss.
| Company | Genetic Approach | Dietary Recommendation Based on | Homepage |
|---|---|---|---|
| Pathway Genomics | SNPs at genetic loci such as ADIPOQ (rs17300539, rs17366568), APOA2 (rs5082), FADS1 (rs174547), FTO (rs9939609, rs1121980), MC4R (rs17782313), PPARG (rs1801282) | Genetic profile matched to a low-fat, low-carbohydrate, Mediterranean or balanced diet, including genetic risks for metabolic health factors (e.g., blood sugar, lipids) | https://www.pathway.com |
| Thinner Gene | SNPs at genetic loci such as FTO, PPARG, PLIN, ADRB2, ADIPOQ, FABP2, PPARG, IRS1, APOA2/5, TCF7L2 | Genetic profile and sensitivity for carbohydrates, fats, and proteins matched with healthy food and fat control | http://www.thinnergene.com |
| Genetic Balance | SNPs at genetic loci associated with fat and carbohydrate metabolism | Genetic make-up matched to good or bad burning of carbohydrates or fats | https://www.genetic-balance.com |
| Bodykey by NUTRILITE | SNPs at genetic loci such as FABP2 (rs1799883), PPARG (rs1801282), ADRB2 (rs1042713), ADRB2 (rs1042714), ADRB3 (rs4994) | Genetic profile matched to diets with different macronutrient compositions | https://www.bodykey.at |
| Nutrigenes | 100 SNPs at genetic loci such as FADS1 | Genetic predisposition to food and nutrient needs, intolerances and sensitivities | http://www.nutrigenes.ch |
| My Kirée | Eight genetic loci associated with body weight | Genetic profile for fat or carbohydrate sensitivity, including supplementation with fat and carbohydrate blockers | https://my-kiree.com |
All homepages were visited on 25th January 2019. ADIPOQ, adiponectin, C1Q, and collagen domain containing; ADRB2/3, adrenoceptor beta 2/3; APOA2/5, apolipoprotein A2/5; FABP2, fatty-acid-binding protein 2; FADS1, fatty-acid desaturase 1; FTO, fat mass and obesity associated; IRS1, insulin receptor substrate 1; LIPC, lipase C, hepatic type; MC4R, melanocortin 4 receptor; PLIN, perilipin 1; PPARG, peroxisome proliferator-activated receptor-gamma; TCF7L2, transcription factor 7 like 2.