Table 1:
Trajectory group-specific clinical characteristics and outcomes
| Holdout cohort 1 (n = 360) | |||||||
| Characteristic | Group 1 (n = 59) | Group 2 (n = 66) | Group 3 (n = 57) | Group 4 (n = 47) | Group 5 (n = 47) | Group 6 (n = 37) | Group 7 (n = 50) |
| Age, years | 61 ± 15 | 58 ± 18 | 58 ± 18 | 61 ± 15 | 62 ± 15 | 53 ± 19 | 57 ± 17 |
| Female sex | 32 (55) | 17 (31) | 16 (40) | 16 (28) | 16 (30) | 22 (50) | 23 (44) |
| Out-of-hospital arrest | 49 (84) | 43 (80) | 32 (80) | 46 (79) | 43 (80) | 38 (86) | 49 (94) |
| Shockable rhythm | 10 (17) | 26 (28) | 21 (52) | 18 (31) | 19 (35) | 7 (16) | 11 (21) |
| PCAC | |||||||
| II | 5 (8) | 25 (46) | 28 (10) | 9 (16) | 23 (43) | 10 (23) | 2 (4) |
| III | 0 (0) | 10 (19) | 4 (10) | 10 (17) | 6 (11) | 2 (5) | 5 (10) |
| IV | 47 (81) | 13 (24) | 5 (13) | 36 (62) | 23 (43) | 30 (68) | 41 (79) |
| Unknown | 6 (10) | 6 (11) | 3 (8) | 3 (5) | 2 (4) | 2 (5) | 4 (8) |
| GWR | |||||||
| <1.2 | 26 (45) | 0 (0) | 1 (3) | 5 (9) | 0 (0) | 1 (2) | 7 (13) |
| 1.2 to <1.3 | 8 (14) | 8 (15) | 6 (15) | 16 (28) | 14 (26) | 13 (30)) | 12 (23) |
| 1.3 to <1.4 | 12 (21) | 17 (31) | 13 (33) | 18 (31) | 23 (43) | 16 (36) | 20 (38) |
| ≥1.4 | 7 (12) | 16 (30) | 10 (25) | 9 (16) | 11 (20) | 7 (16) | 9 (17) |
| Missing | 5 (9) | 13 (24) | 10 (25) | 10 (17) | 6 (11) | 7 (16) | 4 (8) |
| Awaked and survived | 0 (0) | 39 (59) | 39 (68) | 6 (13) | 21 (45) | 7 (19) | 0 (0) |
| Holdout cohort 2 (n = 363) | |||||||
| Characteristic | Group 1 (n = 58) | Group 2 (n = 54) | Group 3 (n = 40) | Group 4 (n = 58) | Group 5 (n = 54) | Group 6 (n = 44) | Group 7 (n = 52) |
| Age, years | 60 ± 18 | 58 ± 14 | 49 ± 16 | 60 ± 18 | 58 ± 14 | 51 ± 15 | 56 ± 16 |
| Female sex | 22 (38) | 20 (30) | 22 (39) | 13 (28) | 15 (32) | 16 (43) | 21 (42) |
| Out-of-hospital arrest | 54 (92) | 49 (74) | 47 (82) | 32 (68) | 36 (77) | 35 (95) | 46 (42) |
| Shockable rhythm | 10 (17) | 31 (47) | 28 (49) | 6 (13) | 24 (51) | 13 (35) | 11 (22) |
| PCAC | |||||||
| II | 4 (7) | 26 (39) | 29 (51) | 9 (19) | 22 (47) | 8 (23) | 8 (16) |
| III | 3 (5) | 17 (26) | 11 (9) | 8 (17) | 8 (17) | 3 (8) | 0 (0) |
| IV | 49 (83) | 19 (29) | 10 (18) | 25 (53) | 15 (32) | 25 (68) | 37 (74) |
| Unknown | 3 (5) | 4 (6) | 7 (12) | 5 (11) | 2 (4) | 1 (3) | 5 (10) |
| GWR | |||||||
| <1.2 | 15 (25) | 1 (2) | 3 (5) | 10 (21) | 7 (15) | 7 (19) | 5 (10) |
| 1.2 to <1.3 | 16 (27) | 9 (14) | 5 (9) | 7 (15) | 12 (26) | 8 (22) | 12 (24) |
| 1.3 to <1.4 | 13 (22) | 30 (45) | 17 (30) | 14 (30) | 16 (34) | 16 (43) | 19 (38) |
| ≥1.4 | 5 (8) | 12 (18) | 19 (33) | 10 (21) | 9 (19) | 4 (11) | 8 (16) |
| Missing | 10 (17) | 14 (21) | 13 (23) | 10 (21) | 7 (15) | 7 (19) | 5 (10) |
| Awaked and survived | 0 (0) | 31 (57) | 30 (75) | 5 (9) | 16 (30) | 4 (9) | 0 (0) |
Data are presented as mean ± standard deviation or number (percent). Abbreviations: PCAC - Pittsburgh Cardiac Arrest Category; GWR - Grey matter to white matter ratio of Hounsfield units.