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. 2019 Mar 14;19(5):3604–3614. doi: 10.3892/mmr.2019.10022

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Copyright: © Cao et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 8. — The effect of knockdown of ETS1 on cell migration and invasion in A549 and H1299 cells. Cell migration was detected by wound healing assay following transfection with si-ETS1 or an miR-512-5p inhibitor in the presence of si-ETS1 in (A) A549 and (B) H1299 cells. Cell invasion was detected by Transwell assay following transfection with si-ETS1 or an miR-512-5p inhibitor in the presence of si-ETS1 in (C) A549 and (D) H1299 cells. MMP-2 and MMP-9 were detected by western blot analysis following transfection with si-ETS1 or an miR-512-5p inhibitor in the presence of si-ETS1 in (E) A549 and (F) H1299 cells. Data are presented as mean ± standard deviation. **P<0.01 vs. NC; ^##P<0.01 vs. si-ETS1. ETS1, E26 transformation specific-1; si, small interfering; miR, microRNA; NC, negative control; MMP, matrix metalloproteinase; inh, inhibitor.