Table 1. Optimization of reaction conditions.

Entry a	Catalyst	Oxidant	Solv. b	T [°C]	Result c
1	Pd(OAc)2	None	ACN	25	N.R.
2	None	AgOAc	ACN	25	N.R.
3	Pd(OAc) 2	AgOAc	ACN	25	86%
4	Pd(OAc)2	AgOAc	ACN	60	83%
5	Pd(OAc)2	AgOAc	THF	25	32%
6	Pd(OAc)2	AgOAc	DCE	25	10%
7	Pd(OAc)2	AgOAc	DMA	25	72%
8	Pd(OAc)2	Cu(OAc)2	ACN	25	0
9	Pd(OAc)2	BQ	ACN	25	30%

^a 1a (0.15 mmol), Pd(OAc)₂ (0.015 mmol), oxidant (1.5 mmol), in 4 mL of solvent.

^bACN = acetonitrile, DMA = dimethylacetamide, DCE = 1,2-dichloroethane, THF = tetrahydrofuran.

^cIsolated yields after purification by silica gel chromatography.