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. 2019 Mar 21;11(3):140. doi: 10.3390/pharmaceutics11030140

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© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Spatial distribution of the concentrations of active substance at different time intervals: (a) case $c_{1} < c_{0}$ , transfer into the membrane; (b) case $c_{1} > c_{0}$ , transfer out of the membrane.