Figure 1.

The cardio-protective and anticancer properties of resveratrol. Resveratrol has been shown to possess both cardio-protective and anticancer properties in preclinical studies through a number of molecular mechanisms. AMPK, Adenosine Monophosphate-Activated Protein Kinase; Bax, BCL (B Cell Lymphoma)-Associated X; EMT, Epithelial Mesenchymal Transition; GSH, Glutathione; IL-6, Interleukin-6; MAPK, Mitogen-activated protein kinase; MDR1, Multidrug Resistance-1; MRP1, Multidrug resistance-associated protein-1; NF-κB, nuclear factor kappa B; P-gp, P-glycoprotein; STAT3, Signal transducer and activator of transcription 3; SIRT1, Sirtuin 1; SOD, Superoxide Dismutase; TNF-α, Tumor Necrosis Factor-alpha; ↑, increase; and ↓, decrease.