Table 1.
Collapsed homologous group descriptions $.
| Alpha Code | Numerical Code | Annotated arCOG Function $$ | arCOG Number |
|---|---|---|---|
| A | cHG_021 | T_I_M | arCOG02632 |
| B | cHG_024 | T_I_M | arCOG05282 |
| C | cHG_018 | T_I_R | arCOG00880 |
| D | cHG_034 | T_I_R | arCOG00879 |
| E | cHG_045 | T_I_R | arCOG00878 |
| F | cHG_006 | T_I_S | arCOG02626 |
| G | cHG_025 | T_I_S | arCOG02628 |
| H | cHG_036 | probable_T_II_M | arCOG00890 |
| I | cHG_001 | T_II_M | arCOG02635 |
| J | cHG_003 | T_II_M | arCOG02634 |
| K | cHG_011 | T_II_M | arCOG04814 |
| L | cHG_033 | T_II_M | arCOG03521 |
| M | cHG_007 | T_II_R | arCOG11279 |
| N | cHG_013 | T_II_R | arCOG11717 |
| O | cHG_023 | T_II_R | arCOG03779 |
| P | cHG_029 | T_II_R | arCOG08993 |
| Q | cHG_042 | Adenine_DNA_methylase_probable_T_III_M | arCOG00108 |
| R | cHG_008 | T_III_R | arCOG06887 |
| S | cHG_009 | T_III_R_probable | arCOG07494 |
| T | cHG_014 | Adenine_DNA_methylase | arCOG00889 |
| U | cHG_022 | DNA_methylase | arCOG00115 |
| V | cHG_027 | DNA_methylase | arCOG00129 |
| W | cHG_031 | dam_methylase | arCOG03416 |
| X | cHG_035 | probable_RMS_M | arCOG08990 |
| Y | cHG_044 | dcm_methylase | arCOG04157 |
| Z | cHG_048 | Adenine_DNA_methylase | arCOG02636 |
| AA | cHG_010 | RNA_methylase | arCOG00910 |
| AB | cHG_040 | SAM-methylase | arCOG01792 |
| AC | cHG_012 | RestrictionEndonuclease | arCOG05724 |
| AD | cHG_038 | PredictedRestrictionEndonuclease | arCOG06431 |
| AE | cHG_015 | HNH_endonuclease | arCOG07787 |
| AF | cHG_019 | Endonuclease | arCOG02782 |
| AG | cHG_020 | Endonuclease | arCOG02781 |
| AH | cHG_004 | HNH_endonuclease | arCOG09398 |
| AI | cHG_037 | HNH_nuclease | arCOG05223 |
| AJ | cHG_039 | HNH_nuclease | arCOG03898 |
| AK | cHG_041 | HNH_nuclease | arCOG08099 |
| AL | cHG_046 | MBF1 | arCOG01863 |
| AM | cHG_028 | CBS_domain | arCOG00608 |
| AN | cHG_005 | MarR | arCOG03182 |
| AO | cHG_030 | ParB-like nuclease | arCOG01875 |
| AP | cHG_016 | GVPC | arCOG06392 |
| AQ | cHG_002 | ASCH domain RNA binding | arCOG01734 |
| AR | cHG_017 | Uncharacterized | arCOG10082 |
| AS | cHG_026 | Uncharacterized | arCOG13171 |
| AT | cHG_032 | Uncharacterized | arCOG08946 |
| AU | cHG_043 | Uncharacterized | arCOG08856 |
| AV | cHG_047 | Uncharacterized | arCOG04588 |
$: A listing of associated Gene Ontology terms and gene family descriptions is available in Table S2. $$: T_I and T_II denote type I and type II restriction enzymes, respectively. M, R, and S denote the methylase, restriction endonuclease, and specificity subunits, respectively.