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Histone-associated DNA fragments released from A498 RCC incubated for 1 h with curcumin (0–0.4 µg/mL) and irradiated with 5500 lx visible light for 5 min (grey) or kept light protected (black). Twenty-four hours later, cell supernatants were prepared. The positive control was incubated with 1 μM staurosporine (set to 100%). Each column represents the mean ± S.D. of a representative experiment done in triplicate. * indicates significant difference to cells with no curcumin (0 µg/mL).
