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. 2019 Mar 19;24(6):1080. doi: 10.3390/molecules24061080

Scheme 2.

Scheme 2

Synthetic route for 3,5-diaminopyrazole derivatives 47. Reagents and Conditions: (a) N2H4·H2O/EtOH-pyridine/reflux 2 h; (b) EtOH-pyridine/reflux 15 h; (c) 2b/PhNHNH2/EtOH-pyridine/reflux 3 h; (d) AcOH/reflux 10 h.