Table 4.
The IC50 (µg) of the new tested chemicals compounds against different tumor cell lines.
| Compound | IC50 (μg/mL) | ||
|---|---|---|---|
| MCF-7 | HepG2 | HCT-116 | |
| 2a | 1.3 ± 0.7 | 0.5 ± 0.2 | 1.2 ± 0.1 |
| 2b | 0.5 ± 0.04 | 1.1 ± 0.3 | 0.5 ± 0.2 |
| 2c | 5.9 ± 0.2 | 9.8 ± 0.5 | 1.2 ± 0.12 |
| 3a | 18.8 ± 1.5 | 6.1 ± 1.1 | 19.1 ± 3.1 |
| 3b | 19.4 ± 2.6 | 19.3 ± 5.7 | 27.8 ± 2.6 |
| 4a | 32.1 ± 1.8 | 6.7 ± 0.9 | 11.5 ± 1.1 |
| 4b | 1.7 ± 0.2 | 1.1 ± 0.1 | 1.1 ± 0.08 |
| 5a | 24.6 ± 3.2 | 73.6 ± 3.1 | 24.1 ± 0.7 |
| 5b | 2.8 ± 0.7 | 0.9 ± 0.1 | 3.7 ± 0.7 |
| 7a | 16.3 ± 0.6 | 14.3 ± 2.6 | 14.1 ± 1.9 |
| 7b | 20.8 ± 1.7 | 21.3 ± 3.1 | 15.7 ± 1.7 |
| 8a | 10.7 ± 0.3 | 4.9 ± 0.6 | 11.1 ± 0.5 |
| 8b | 0.3 ± 0.01 | 0.6 ± 0.2 | 0.4 ± 0.02 |
| 9a | 106 ± 4.3 | 226.9 ± 3.2 | 103.8 ± 5.1 |
| 9b | 38.5 ± 0.5 | 18.9 ± 0.8 | 31.1 ± 2.5 |
| 10a | 10.1 ± 2.6 | 7.5 ± 0.7 | 12.9 ± 1.6 |
| 10b | 43.9 ± 1.1 | 85.9 ± 3.4 | 29.4 ± 2.4 |
| 11a | 19.8 ± 1.9 | 26.6 ± 4.4 | 25.9 ± 1.7 |
| 11b | 4.5 ± 0.4 | 3.9 ± 0.4 | 2.7 ± 0.6 |
| 12a | 18.8 ± 1.7 | 31.4 ± 2.7 | 46.1 ± 5.9 |
| 12b | 1.4 ± 0.03 | 3.4 ± 0.6 | 2.4 ± 0.4 |
| 13 | 4.2 ± 0.2 | 4.1 ± 0.3 | 5.3 ± 0.8 |
| Doxorubicin | 1.2 ± 0.2 | 0.9 ± 0.3 | 1.6 ± 0.2 |