Table 2.
Genotypic and allelic frequencies of single nucleotide polymorphisms (SNPs) in MTHFR, TCNII, MTR and MTRR genes in the whole studied group (n = 323).
| SNP | Genotype | Allele Frequency (%) | |||
|---|---|---|---|---|---|
| MTHFR | CC | CT | TT | C | T |
| C677T (n = 565) | 295 (52.2%) | 218 (38.6%) | 52 (9.2%) | 71.5 | 28.5 |
| MTHFR | AA | AC | CC | A | C |
| A1298C (n = 565) | 301 (53.3%) | 196 (34.7%) | 68 (12.0%) | 70.6 | 29.4 |
| TCNII | AA | AG | GG | A | G |
| A67G (n = 301) | 252 (83.7%) | 43 (14.3%) | 6 (2%) | 90.9 | 9.1 |
| TCNII | CC | CG | GG | C | G |
| C776G (n = 292) | 83 (28.4%) | 141 (48.3%) | 68 (23.3%) | 52.6 | 47.4 |
| MTR | AA | AG | GG | A | G |
| A2756G (n = 218) | 128 (58.7%) | 82 (37.6%) | 8 (3.7%) | 77.5 | 22.5 |
| MTRR | AA | AG | GG | A | G |
| A66G (n = 246) | 75 (30.5%) | 114 (46.3%) | 57 (23.2%) | 53.7 | 46.3 |