Figure 2.

The complex summary of the beneficial effect of treatment with curcumin in esophageal and gastric protection: It involves the amelioration of damage induced by reflux esophagitis and incidence of Barrett’s esophagus, attenuation of inflammation, prevention of gastric damage formation, the anti-Helicobacter pylori activity, and an improvement of communication between gut function and the brain (gut–brain axis) by this turmeric derivative to facilitate local microvascular vasodilation and an increase in organ blood flow, gastroprotection, and ulcer healing.