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The relationship between the F index and the aberrant methylation of tumor-related genes. The F index of the lesions which exhibited the aberrant methylation of p16 was significantly higher than that of tumors without the aberrant methylation of p16 (A). Conversely, there was no significant difference in the F index between lesions with and without the aberrant methylation of Apc (B), hMLH1 (C), E-cadherin (D), and Runx3 (E).
