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. 2019 Mar 20;24(6):1106. doi: 10.3390/molecules24061106

Figure 4.

Figure 4

A representative case of colon cancer with the aberrant methylation of the p16 and E-cadherin genes. A conventional colonoscopy revealed an elevated lesion (A). AFI detected the lesion as a strong magenta area (B). A high N/C ratio (0.67) was observed on the histological specimen of the lesion, which was diagnosed to be a cancer in situ (C). MS-PCR showed the aberrant methylation of the p16 and E-cadherin gene promoters (D).