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. 2019 Apr 18;26:27. doi: 10.1186/s12929-019-0521-1

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Lasting deleterious influence on dendritic maturation after hypoxic challenge. (a) Representative images of the retroviral labeled newly generated neurons born at different time points (7, 14, 21 or 28 days) after MCAO surgery and imaged for their dendritic elaboration at 14dpi. The scale bar is 25 μm. (b) Quantification of total dendritic length of individual 14 dpi newborn neurons born at 7, 14, 21 or 28 days after MCAO surgery. (c) Quantification of the number of dendritic branches from individual 14 dpi newborn neurons born at 7, 14, 21 or 28 days after MCAO surgery. Data are presented as mean ± SEM. n = 20 to 40 cells from four mice, two-tailed unpaired t-test. * p < 0.05 compared to sham-operated control. “ns” represents no significant