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. 2019 Mar 14;19(5):3743–3755. doi: 10.3892/mmr.2019.10037

Figure 1.

Figure 1.

Effects of β-estradiol supplement on tail systolic arterial pressure in SHR. Tail systolic arterial pressure of the SHR group significantly increased in comparison with the WKY group. Compared with SHR without β-estradiol treatment, chronic subcutaneous injection of 20 µg/kg/day β-estradiol for 5 weeks significantly attenuated hypertension in the SHR + E group. Values are presented as the mean ± standard error, n=6. **P<0.01 (P=0.0061), WKY vs. SHR and #P<0.05 (P=0.0447), SHR vs SHR + E. SHR, spontaneously hypertensive rat; WKY, Wistar-Kyoto rats; SHR + E, SHR + β-estradiol.