Table A2.
Quality assessment of included cell culture studies (adapted from WCRF/UoB recommendations) [22].
| Author, Year | Source 1 | Experimental Conditions | Selective Reporting 6 | Total | |||
|---|---|---|---|---|---|---|---|
| Culture Conditions 2 | Replicates 3 | Controls 4 | Multiple Cell Lines 5 | ||||
| Fu, 2014 [44] | 1 | 1 | 0 | 1 | 1 | 1 | 5 |
| Gong, 2016 [40] | 1 | 1 | 1 | 1 | 1 | 1 | 6 |
| Gunasekera, 2007 [41] | 1 | 1 | 1 | 1 | 1 | 1 | 6 |
| Ivanov, 2007 [32] | 1 | 1 | 0 | 1 | 1 | 0 | 4 |
| Linnewiel-Hermoni, 2015 [33] | 1 | 1 | 1 | 1 | 1 | 1 | 6 |
| Liu, 2006 [34] | 1 | 1 | 1 | 0 | 1 | 1 | 5 |
| Liu, 2008 [35] | 1 | 1 | 1 | 1 | 1 | 1 | 6 |
| Peternac, 2008 [36] | 1 | 1 | 1 | 1 | 1 | 1 | 6 |
| Rafi, 2013 [37] | 1 | 1 | 1 | 1 | 0 | 1 | 5 |
| Richards, 2003 [38] | 1 | 0 | 1 | 1 | 0 | 0 | 3 |
| Tang, 2005 [42] | 1 | 1 | 1 | 1 | 1 | 1 | 6 |
| Tang, 2011 [43] | 1 | 1 | 1 | 1 | 1 | 0 | 5 |
| Zhang, 2010 [39] | 1 | 1 | 0 | 1 | 0 | 0 | 3 |
Studies are given a score of 0 or 1 for each of the following parameters (a score of 0 was given for a lack of criteria fulfillment or failure to report): 1 cell lines are independently validated; 2 comparable culture conditions to other studies; 3 experiment performed in replicate(s); 4 appropriate controls included; 5 more than one cell line used; 6 all experimental results are reported (a score of 0 was given for missing statistical data).