Figure 5.
Effects of hesperetin against LPS-induced oxidative stress in the cortical and hippocampal region of mouse brains and in HT-22 cells: (A,B) the analysis of the generation of ROS and LPO production in vivo in the mouse brain (cortex and hippocampus regions); (C) Western blot analysis of Nrf2 and HO-1 in the cortex and hippocampus of adult mouse brains. The data are presented as the mean ± SEM of 8–10 mice per group and are representative of three independent experiments, * p ≤ 0.05, ** p ≤ 0.01.