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. 2019 Apr 17;38:168. doi: 10.1186/s13046-019-1147-6

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 7 — Safety evaluation of CAR-T therapy. a. H&E staining shows that there is no obvious off-target toxicity against mouse major organs. × 100 magnifications. Scale bar, 200 μm. b. CD166.BBζ CAR-T cells show no cytolytic activity against healthy HL-7702 cells. hFOB 1.19 and HFL1 cell lines are sensitive to CD166.BBζ CAR-T cells in vitro