Table 1.
Clinical characteristics of patients with septic shock
| Parameters | Patients with septic shock (n = 31) |
|---|---|
| Sex, male | 19 (62%) |
| Age, years | 72 [63.5–76.5] |
| SAPS II | 60 [49.5–75.5] |
| SOFA (n = 29) | 8 [8–11] |
| Charlson co-morbidity score | |
| 0 | 4 (13%) |
| 1 | 13 (42%) |
| >1 | 14 (45%) |
| Initial infection | |
| Abdominal infection | 14 (45%) |
| Urinary infection | 4 (13%) |
| Pneumopathy | 1 (3%) |
| Other | 12 (39%) |
| Type of admission | |
| Medical | 19 (61.5%) |
| Emergency surgery | 11 (35.5%) |
| Elective surgery | 1 (3%) |
| Microbiological documentation | |
| Gram-negative | 8 (26%) |
| Gram-positive | 8 (26%) |
| Other | 1 (3%) |
| Non-documented | 14 (45%) |
| Mortality at day 28 | 8 (27%) |
| Nosocomial infections | 1 (3%) |
| ICU length of stay, days | 6 [5–13] |
| Lactate at admission, mmol/L (n = 28) | 3.35 [2.5–5.83] |
| Lymphocytes at day 3, G/L (n = 21) | 1.05 [0.55–1.45] |
| mHLA-DR at day 3, AB/C | 7748 [3358–15,200] |
| Percentage of Treg cells among CD4+ cells at day 3 (n = 20) | 5.0 [3.0–6.8] |
For clinical parameters, categorical data are presented as numbers of cases and percentages of the total population in brackets. Continuous data and biological parameters are presented as medians and interquartile ranges [Q1–Q3]. SAPS II (Simplified Acute Physiology Score II) was calculated on admission. SOFA (Sequential Organ Failure Assessment) score was measured after 24 h of intensive care unit (ICU) stay. mHLA-DR (AB/C): number of anti-HLA-DR antibodies bound per monocyte. Regulatory T (Treg): CD4+CD25highCD127low Treg cells