Table 1.
Participant demographics and outcomes
| Variable | Total participants (n = 1657) | Analytical sample (n = 1338) | Excluded sample (n = 319) | Included vs excluded p value |
|---|---|---|---|---|
| Demographics | ||||
| Male, % (n) | 54.7 (907) | 56.2 (753) | 48.3 (154) | < 0.01 |
| Age in years, mean (SD) | 60.0 (18.9) | 58.9 (19.0) | 64.8 (17.7) | < 0.01 |
| Main outcomes | ||||
| MV-free days, mean (SD) | 10.1 (10.7) | 9.6 (10.4) | 12.2 (11.7) | < 0.01 |
| ICU-free days, mean (SD) | 7.3 (8.9) | 6.7 (8.5) | 9.9 (10.1) | < 0.01 |
| Hospital-free days, mean (SD) | 11.1 (16.6) | 10.8 (16.4) | 12.4 (17.5) | <0.05 |
| 90-day mortality, % (n)* | 49.1 (810) | 50.1 (669) | 44.5 (141) | 0.07 |
| Clinical parameters | ||||
| APACHE II score, mean (SD) | 24.0 (7.8) | 24.1 (7.9) | 23.6 (7.5) | 0.22 |
| APACHE III score, mean (SD) | 82.7 (28.1) | 83.6 (28.3) | 78.9 (26.9) | < 0.01 |
| SOFA score, mean (SD) | 9.5 (3.5) | 9.7 (3.5) | 8.8 (3.6) | < 0.01 |
| Prevalence of ARDS, % (n)** | 17.5 (289) | 19.7 (262) | 8.5 (27) | < 0.01 |
| Hospital admission type*** | 0.56 | |||
| Medical, % (n) | 72.3 (1196) | 72.4 (968) | 71.7 (228) | |
| Trauma, % (n) | 10.7 (177) | 11.6 (155) | 6.9 (22) | |
| Surgical (scheduled), % (n) | 3.5 (58) | 3.1 (42) | 5.0 (16) | |
| Surgical (unscheduled), % (n) | 10.8 (178) | 9.8 (131) | 14.8 (47) | |
| Other, % (n) | 2.8 (46) | 3.1 (41) | 1.6 (5) | |
*From the 1657 participants, there were 6 participants whose death by 90 days was not recorded. Percentages (%) are obtained from all the participants whose status was known by 90 days
**From the 1657 participants there were 8 participants whose ARDS diagnosis was not determined. Percentages are obtained based on all participants where a yes/no ARDS diagnosis was recorded.
***From the 1657 participants there were 2 participants whose admission type was not obtained. Percentages are obtained from all those participants whose admission was obtained