Table 2.

Sedation status associated with 90-day mortality

Variable	Single variable	p value	Multivariable	p value
Age	1.62 (1.36–1.93)	< 0.001	1.31 (1.07–1.61)	< 0.01
Sex (males are reference)	0.94 (0.76–1.17)	0.59	0.98 (0.76–1.25)	0.86
APACHE III	2.24 (1.90–2.64)	< 0.001	1.98 (1.62–2.40)	< 0.001
% Days with deep sedation	4.70 (3.76–5.88)	< 0.001	5.42 (4.23–6.95)	< 0.001
% Days with agitation	1.57 (0.32–7.71)	0.58	39.9 (6.53–243)	< 0.001
Hospital site 1 (reference)	1.00	1.00	1.00
Hospital site 2	0.70 (0.52–0.96)	0.03	0.63 (0.43–0.90)	0.01
Hospital site 3	0.66 (0.47–0.93)	0.02	0.79 (0.53–1.18)	0.25
Hospital site 4	0.58 (0.43–0.78)	< 0.001	0.45 (0.32–0.62)	< 0.001
Hospital site 5	1.35 (0.89–2.06)	0.16	0.93 (0.57–1.54)	0.78