Table 2.
Univariate and multivariate Fine-Gray models for the event emergence from altered consciousness state
| Univariate | Multivariate † | |||
|---|---|---|---|---|
| HR (95% CI) | C Index | HR (95% CI) | C Index | |
| Age (years) | 1.01 (0.99–1.03) | 0.313 | 1.00 (0.98–1.02) | |
| Male (vs female) | 0.76 (0.41–1.42) | 0.585 | 0.71 (0.36–1.38) | |
| MCS (vs VS) | 9.36 (4.45–19.69)* | 0.613 | 9.68 (4.46–21.01)* | 0.708 |
| CRS | 1.36 (1.25–1.48)* | 0.668 | 1.38 (1.26–1.52)* | 0.699 |
| Aetiology | 0.554 | |||
| Anoxic (vs. Traumatic) | - § | – | ||
| Vascular (vs. Traumatic) | 1.25 (0.66–2.38) | 1.00 (0.46–2.18) | ||
| IRU days | 0.588 | |||
| 31–59 (vs < 31) | 0.82 (0.43–1.56) | 0.56 (0.28–1.17) | ||
| 60–89 (vs < 31) | 0.43 (0.15–1.27) | 0.36 (0.12–1.11) | ||
| Tree Subgroups | 0.604 | |||
| Subgroup B (vs A) | 6.27 (0.61–842.86) | |||
| Subgroup C (vs A) | 10.33 (1.22–1346.99)* | |||
| Subgroup D (vs A) | 33.67 (4.57–4294.73)* | |||
| Subgroup E (vs A) | 81.77 (11.01–10,442.44)* | |||
† Both multivariate models have been developed with covariates Age, Sex, Aetiology, ICU days and, alternatively, MCS/VS state or CRS value at admission
*: p < 0.05; § p < 0.05 for the k-sample test comparing the subdistribution for the event emergence
HR: Hazard-Ratio; IRU: Intensive Rehabilitation Unit; MCS: minimally consciousness state; VS: Vegetative State; CRS: Coma-Recovery Scale