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. 2001 Nov 20;98(25):14559–14564. doi: 10.1073/pnas.251540598

Figure 5.

Figure 5

Analysis of the IL-2 and IL-15R complex in the Tax-specific CD8 cells and total CD8 cells. Uncultured PBMC (day 0) of five normal donors and five HAM/TSP patients (pt#) studied here were stained with tetramer-Tax, an anti-CD8 antibody, and antibodies against different chains of the IL-2Rs or IL-15Rs (CD25 or IL-2Rα, CD122 or IL-2/15Rβ, CD132 or γc, and IL-15Rα), and an appropriate isotype control antibody. The Tax-specific CD8 cells were gated, and expression of each receptor subunit by these cells was examined. In addition, the expression of IL-2Rs and IL-15Rs by total CD8 cells was analyzed. The data presented for the normal donor are representative of five different normal donors examined.