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. 2019 Apr 17;10:121. doi: 10.1186/s13287-019-1226-9

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — rMSCs increased RGC survival up to 240 days after crush. a–e Confocal images of flat-mounted retinas. Control retina (contralateral eye) shows numerous Tuj1⁺ cells and intact axon bundles. a, c Vehicle-injected retinas; b, d rMSC-treated retinas. Arrows point to cell bodies and arrowheads to axon bundles. f, g In rMSC-injected animals, surviving RGCs were significantly increased in both time points after crush. *P < 0.05, **P < 0.01; unpaired t test. Scale bar 50 μm