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H2O2 treatment downregulates Creb expression in PDLSCs. (A) Reverse transcription-quantitative polymerase chain reaction and (B) western blot analysis of Creb expression after 24 h of treatment with H2O2 at the indicated concentrations. PDLSCs treated with an equivalent volume of PBS were used as the control. *P<0.05, **P<0.01, ***P<0.001 vs. respective control. PDLSCs, periodontal ligament stem cells; Creb, cAMP responsive element binding protein.
