Table IV.

Summary of the 16 tRFs downregulated in patients with moyamoya disease vs. healthy controls.

tRF ID	Mintbase ID	tRF sequence (5′-3′)	Amino acid-anticodon	Fold change	P-value
AS-tDR-007510	N/A	ACTCTGGACTCTGAATCT	Gln-CTG	297.887	0.016055
AS-tDR-000924	tRF-16-PS5P4PE	GCCCGGATAGCTCAGT	Lys-TTT	260.969	0.037030
AS-tDR-003801	tRF-17-MMUKLYK	CGGTCTAAGGCGCTGCG	Leu-CAG	186.513	0.032042
AS-tDR-011424	N/A	ATATCCAACCTTCGGCTATAGGG	Thr-CGT	8.018	0.006046
AS-tDR-011366	tRF-19-WB86N7HU	TCGAATCCCACTTCTGACA	Leu-CAG & Leu-CAA	7.902	0.023668
AS-tDR-005697	tRF-18-BS6PDFD2	AACCGGGCAGAAGCACCA	Val-CAC	7.168	0.010754
AS-tDR-000053	tRF-31-79MP9P9NH57SD	GTTTCCGTAGTGTAGTGGTTATCACGTTCGC	Val-AAC	6.730	0.011393
AS-tDR-009236	N/A	GGCTCGAAGGACTTCGTCTGTAA	Tyr-GTA	5.578	0.031881
AS-tDR-009369	tRF-21-WD8YQ84VD	TCGACTCCTGGCTGGCTCGCC	Arg-ACG	5.389	0.042221
AS-tDR-001449	tRF-32-79MP9P9NH57SJ	GTTTCCGTAGTGTAGTGGTTATCACGTTCGCC	Val-AAC & Val-CAC	5.162	0.016935
AS-tDR-001400	tRF-32-6978WPRLXN4VQ	GGCTCGTTGGTCTAGGGGTATGATTCTCGCTT	Pro-CGG & Pro-TGG & Pro-AGG	5.159	0.006515
AS-tDR-011405	N/A	TTGAGATACTGAGTAGTCTGGTG	Arg-TCG	4.422	0.016291
AS-tDR-000009	tRF-31-P4R8YP9LON4VD	GCATGGGTGGTTCAGTGGTAGAATTCTCGCC	Gly-GCC	3.029	0.005745
AS-tDR-007276	N/A	GTTTCCGTAGTGTAGTGGTTATCACGTTCGCT	Val-CAC & Val-AAC	2.853	0.048408
AS-tDR-009331	N/A	TCGACTCCTGGCTGGCTCG	Arg-ACG	2.749	0.004973
AS-tDR-001273	tRF-35-86V8WPMN1E8Y7Z	TCCCATATGGTCTAGCGGTTAGGATTCCTGGTTTT	Glu-TTC	2.377	0.033231

tRFs, transfer RNA-derived fragments.