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. 2019 Mar 21;19(5):4388–4400. doi: 10.3892/mmr.2019.10076

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Copyright: © Jia et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 6. — Association between miR-146a-5p expression and the protein levels of CXCR4 and Col II. Chondrocytes were separately transfected with miR-146a-5p mimics, miR-146a-5p inhibitors and NC for 48 h using Lipofectamine^® 3000. Following stimulation with 100 ng/ml SDF-1 for 2 days, cells were harvested to evaluate the protein levels of CXCR4 and Col II. (A) Represent western blot showing the protein levels of CXCR4 and Col II. (B and C) Summary data from 3 independent western blot analysis experiments on the protein levels of (B) CXCR4 and (C) Col II. **P<0.01 and ***P<0.001 vs. the corresponding control group. miRNA, miRNA; Col II, type II collagen; CXCR4, C-X-C chemokine receptor type 4; SDF-1, stromal cell-derived factor 1; NC, negative control.