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. 2019 Apr 18;20(Suppl 4):152. doi: 10.1186/s12859-019-2688-6

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© The Author(s) 2019

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License(http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver(http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 10 — Comparison of signature refitting versus de novo inference. The figure plots for all 435 tumors the explained variance of the exposures as predicted by decompTumor2Sig and originally determined by pmsignature