Table 2.
Uniform mutation frequencies according to the probabilistic Shiraishi model of mutational signatures, exemplified by the same 6+4∗4+2=24 parameters as in Table 1
Nucleotide change (central base) | Flanking bases | Transcription strand | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
C >A | C >G | C >T | T >A | T >C | T >G | Position | A | C | G | T | Plus strand | Minus strand |
1/6 | 1/6 | 1/6 | 1/6 | 1/6 | 1/6 | -2 | 1/4 | 1/4 | 1/4 | 1/4 | 1/2 | 1/2 |
-1 | 1/4 | 1/4 | 1/4 | 1/4 | ||||||||
+1 | 1/4 | 1/4 | 1/4 | 1/4 | ||||||||
+2 | 1/4 | 1/4 | 1/4 | 1/4 |