T cells infiltrates within treated prostate tissues are comprised
predominantly of CD4+ and a lesser amount of CD8+ T cells, including
cells exhibiting markers of activation and cytotoxic potential.
Immunochemical staining of CD3+ T cell-rich prostate infiltrates within
treated prostate tissues demonstrates relatively greater numbers of
CD4+ (A) compared with CD8+ T cells
(B). Figures are at final ×400. Further
staining of these sites reveals moderate numbers of cells expressing
activation markers, IFN-γ (C), proliferative marker,
Ki67 (D), IL2
receptor, CD25 (E), and cytotoxic granule-associated
protein, TIA-1 (F). (×800.)