Table 1.
Cases N=2,703 |
Controls N=3,254 |
|||
---|---|---|---|---|
N | %a | N | %a | |
Study | ||||
San Francisco Bay Area Breast Cancer Study (SFBCS) | 980 | 36 | 1,357 | 42 |
Northern California Breast Cancer Family Registry (NC-BCFR) | 262 | 10 | 63 | 2 |
4-Corners Breast Cancer Study (4-CBCS) | 596 | 22 | 831 | 26 |
Mexico Breast Cancer Study (MBCS) | 865 | 32 | 1,003 | 31 |
Estrogen receptor (ER) and progesterone receptor (PR) statusb | ||||
ER+ and/or PR+ | 1,139 | 62 | ||
ER-PR- | 382 | 21 | ||
Unknown | 317 | 17 | ||
Age (years) | ||||
< 40 | 305 | 11 | 337 | 10 |
40–44 | 386 | 14 | 472 | 15 |
45–49 | 464 | 17 | 537 | 17 |
50–54 | 428 | 16 | 489 | 15 |
55–59 | 387 | 14 | 448 | 14 |
60–64 | 319 | 12 | 385 | 12 |
≥65 | 414 | 15 | 586 | 18 |
Education | ||||
Some high school or less | 1,425 | 53 | 1,963 | 60 |
High school graduate | 523 | 19 | 558 | 17 |
Some college or higher | 752 | 28 | 731 | 22 |
Unknown | 3 | <1 | 2 | <1 |
Family history of breast cancer in first-degree relatives | ||||
No | 2,333 | 86 | 2,925 | 90 |
Yes | 331 | 12 | 260 | 8 |
Unknown | 39 | 1 | 69 | 2 |
Age at menarche (years) | ||||
<12 | 638 | 24 | 670 | 21 |
12 | 679 | 25 | 732 | 22 |
13 | 633 | 23 | 757 | 23 |
≥14 | 753 | 28 | 1,095 | 34 |
Unknown | 0 | 0 | ||
Hormonal contraceptive use | ||||
Current | 100 | 4 | 92 | 3 |
Former | 1,370 | 51 | 1,551 | 48 |
Never | 1,085 | 40 | 1,463 | 45 |
Unknown | 148 | 5 | 148 | 5 |
Menopausal status | ||||
Premenopausal | 1,073 | 40 | 1,217 | 37 |
Postmenopausal | 1,547 | 57 | 1,928 | 59 |
Unknown | 83 | 3 | 109 | 3 |
Hormone therapy use (postmenopausal women) | ||||
Current | 378 | 24 | 333 | 17 |
Former | 295 | 19 | 510 | 26 |
Never | 874 | 56 | 1,085 | 56 |
Average daily alcohol consumption (grams)c | ||||
0 | 1,762 | 65 | 2,429 | 75 |
0.1–4.9 | 604 | 22 | 519 | 16 |
≥ 5.0 | 303 | 11 | 279 | 1 |
Unknown | 34 | 1 | 27 | 1 |
Body mass index (kg/m2) (premenopausal women)d | ||||
< 25.0 | 340 | 32 | 278 | 23 |
25.0–29.9 | 401 | 37 | 470 | 39 |
≥ 30.0 | 314 | 29 | 451 | 37 |
Unknown | 18 | 2 | 18 | 1 |
Body mass index (kg/m2) (postmenopausal women)d | ||||
< 25.0 | 326 | 21 | 340 | 18 |
25.0–29.9 | 569 | 37 | 712 | 37 |
≥30.0 | 617 | 40 | 838 | 43 |
Unknown | 35 | 2 | 38 | 2 |
Age at first live birth (years) | ||||
<20 | 755 | 28 | 1,096 | 34 |
20–24 | 1,015 | 38 | 1,248 | 38 |
25–29 | 557 | 21 | 614 | 19 |
≥30 | 376 | 14 | 296 | 9 |
Mean | 23.4 | 22.7 | ||
Range | 11–46 | 12–50 | ||
Paritye | ||||
1 | 400 | 15 | 316 | 10 |
2 | 774 | 29 | 755 | 23 |
3 | 688 | 25 | 823 | 25 |
4 | 374 | 14 | 492 | 15 |
5 | 196 | 7 | 319 | 10 |
≥6 | 271 | 10 | 549 | 17 |
Mean | 3.0 | 3.6 | ||
Range | 1–12 | 1–17 | ||
Duration of lifetime breast-feeding (months) | ||||
0 | 783 | 29 | 776 | 24 |
1–6 | 922 | 34 | 964 | 30 |
7–12 | 360 | 13 | 479 | 15 |
13–24 | 343 | 13 | 500 | 15 |
≥25 | 295 | 11 | 535 | 16 |
Mean | 11.0 | 15.9 | ||
Range | 0–166 | 0–188 |
Abbreviations: 4-CBCS, 4-Corners Breast Cancer Study; ER, estrogen receptor; MBCS, Mexico Breast Cancer Study; NC-BCFR, Northern California Breast Cancer Family Registry; PR, progesterone receptor; SFBCS, San Francisco Bay Area Breast Cancer Study.
Percentages may not add up to 100% due to rounding.
Excluding participants in the MBCS for whom data on ER and PR status were not available.
Average daily lifetime consumption for participants in the NC-BCFR, 4-CBCS, MBCS, and SFBCS participants diagnosed/selected into the study after April 1999; and average daily consumption in reference year for SFBCS participants diagnosed/selected into the study before May 1999.
In reference year (calendar year before diagnosis for cases or before interview or selection into the study for controls).
Number of live births.